Indications Of Fresh Frozen Plasma (FFP)
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Single-factor deficiencies.
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Multiple-factor deficiencies, hypo/dysfibrinogenemia, and/or disseminated intravascular coagulopathy
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Thrombotic thrombocytopenic purpura.
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Need for urgent reversal of warfarin effect
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Vitamin K deficiency
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Liver disease, especially in the setting of liver biopsy
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Preparation for invasive bedside procedures
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During intraoperative cardiopulmonary bypass
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For massive transfusion
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Hemorrhagic disease of the newborn
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Inherited deficiencies of clotting factors.
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Coagulopathy and bleeding, or coagulopathy with planned procedure.
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Prevention of red blood cell hemolysis related to red cell T antigen activation
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Hypovolemia
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Plasma exchange.
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Reversal of prolonged INR in the absence of bleeding
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Prevention of intraventricular hemorrhage in preterm infants
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Treatment of neonates with polycythemia
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Wound healing.
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Other inappropriate uses.
In addition, frozen plasma should not be used for
nutritional support, protein-losing states, Guillain-Barré syndrome, acute pancreatitis or burns