Indications Of Fresh Frozen Plasma (FFP)

• Single-factor deficiencies.

• Multiple-factor deficiencies, hypo/dysfibrinogenemia, and/or disseminated intravascular coagulopathy

• Thrombotic thrombocytopenic purpura.

• Need for urgent reversal of warfarin effect

• Vitamin K deficiency

• Liver disease, especially in the setting of liver biopsy

• Preparation for invasive bedside procedures

• During intraoperative cardiopulmonary bypass

• For massive transfusion

• Hemorrhagic disease of the newborn

• Inherited deficiencies of clotting factors.

• Coagulopathy and bleeding, or coagulopathy with planned procedure.

• Prevention of red blood cell hemolysis related to red cell T antigen activation

• Hypovolemia

• Plasma exchange.

• Reversal of prolonged INR in the absence of bleeding

• Prevention of intraventricular hemorrhage in preterm infants

• Treatment of neonates with polycythemia

• Wound healing.

• Other inappropriate uses.

  In addition, frozen plasma should not be used for

  nutritional support, protein-losing states, Guillain-Barré syndrome,  acute pancreatitis or burns